Heated Tobacco Products Create Side-Stream Emissions: Implications for Regulation

Applying toxicological risk assessment principles to constituents of smokeless tobacco products: implications for product regulation.

OBJECTIVE To determine how information on chemical constituents of different smokeless tobacco products (STPs) may be used in cancer risk assessment for regulatory purposes. METHODS This study investigated select STP constituents potentially associated with significant cancer risk by applying a known toxicological risk assessment framework. Cancer risk estimates were obtained for selected con...

Consistency of arsenic speciation in global tobacco products with implications for health and regulation

BACKGROUND Tobacco smoke is a major risk to the health of its users and arsenic is among the components of smoke present at concentrations of toxicological concern. There are significant variations in human toxicity between inorganic and organic arsenic species and the aim of this study was to determine whether there are predictable relationships among major arsenic species in tobacco that coul...

The need for FDA regulation of tobacco products.

An experimental method to study emissions from heated tobacco between 100-200°C

BACKGROUND Cigarette smoke emissions are mainly produced by distillation, pyrolysis and combustion reactions when the tobacco is burnt. Some studies have shown that heating tobacco to temperatures below pyrolysis and combustion temperatures has the potential to reduce or eliminate some toxicants found in cigarette smoke. In this study, we designed a bench-top tube furnace that heats tobacco bet...

Federal regulation of tobacco products and products that treat tobacco dependence: are the playing fields level?